(S)-2-[(tert-Butoxycarbonyl)(methyl)amino]butyric,acid

(S)-2-[(tert-Butoxycarbonyl)(methyl)amino]butyric,acid - Names and Identifiers

Name	Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]methylamino]-, (S)-
Synonyms	N-Boc-(S)-2-(MethylaMino)butyric acid N-Boc-(S)-2-(methylamino)butyric acid (S)-2-[(tert-Butoxycarbonyl)(methyl)amino]butyric,acid (S)-2-((tert-Butoxycarbonyl)(methyl)amino)butanoic acid Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]methylamino]-, (S)- Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]methylamino]-, (2S)-
CAS	101759-74-4

(S)-2-[(tert-Butoxycarbonyl)(methyl)amino]butyric,acid - Physico-chemical Properties

Molecular Formula	C10H19NO4
Molar Mass	217.26
Density	1.089±0.06 g/cm3(Predicted)
Boling Point	312.4±21.0 °C(Predicted)
pKa	4.01±0.10(Predicted)
Storage Condition	2-8°C

(S)-2-[(tert-Butoxycarbonyl)(methyl)amino]butyric,acid - Introduction

N-Boc-(S)-2-methylaminobutyric acid is an organic compound with the following properties:

1. Appearance: A white solid.
2. Chemical structure: It is a product obtained by the reaction of benzene carboxylic acid, dimethyl carbonate anhydride and (S)-2-methylaminobutyric acid.
3. Solubility: It can be dissolved in organic solvents, such as dimethylformamide and dichloromethane.
4. melting point: about 80-82 degrees Celsius.

N-Boc-(S)-2-methylaminobutyric acid is widely used in organic synthesis, especially in chiral synthesis. It can be used as a chiral catalyst intermediate or chiral ligand for the synthesis of chiral compounds. In addition, it can also be used in the synthesis of drugs, pesticides and other compounds containing chiral centers.

A common method for preparing N-Boc-(S)-2-methylaminobutyric acid is to react (S)-2-methylaminobutyric acid with dimethyl carbonic anhydride in the presence of a base to obtain the target product. Then, N-Boc-(S)-2-methylaminobutyric acid can be obtained by reacting with benzenecarboxylic acid and then undergoing a deprotection step.

Regarding safety information, N-Boc-(S)-2-methylaminobutyric acid may be irritating to eyes, skin and respiratory tract, it is necessary to pay attention to protective measures during use, such as wearing protective glasses and gloves. In addition, it should be stored and handled away from ignition and oxidizing agents. If inhalation or contact occurs, seek medical help immediately, and pay attention to cleaning the affected area. When using this compound in the laboratory, it is necessary to strictly follow the corresponding safety procedures.

Last Update：2024-04-09 20:52:54